SculpSure 是用 1030nm 波長的雷射，對著皮膚照射，產生高溫 （hyperthermia ）破壞皮下脂肪。SculpSure 有兩個特徵：一是體外照射，二是高溫雷射。這種二極體雷射可將皮下組織加溫到42-47度Ｃ，藉此破壞細胞，細胞破壞後被人體代謝掉，1-3個月後就可以減少脂肪細胞的數量。
從已發表的文獻看，體外照射不管是雷射、聚焦超音波或冷凍低溫，去除脂肪的效果都不太好。體內照射的，即便是超音波溶脂（如 Vaser 或 Ultraz），或雷射溶脂 （ Smartlipo），如果照完沒有將脂肪吸出來也是看不出明顯的效果。Bingol 2014 等人在其研究報告中認為即便是進入體內照射高能雷射的雷射溶脂，號稱「不必吸出油脂也有效」是沒有科學根據的說法。
認為 SculpSure 體外雷射溶脂有效的醫學文獻報導
目前查到兩篇跟 SculpSure 1060 nm 體外照射雷射的文獻，都說有效。但是我要進一步找論文時就找不到了。所以我不清楚作用機轉和實際治療前後的比較圖。不過以我在溶脂方面的經驗來看，隔著皮膚對脂肪加熱，必須冒著皮膚高溫燙傷的風險，雖然 SculpSure 廠商有在接觸皮膚的地方降溫的設計，應該會增加安全性避免燙傷。不過，在台灣也有一些被「音波拉皮」燙傷的案例，而這種音波拉皮也號稱不會燙傷皮膚。
J Drugs Dermatol. 2018 Jan 1;17(1):106-112.
Safety and Efficacy of a Non-Invasive 1060 nm Diode Laser for Fat Reduction of the Abdomen.
Bass LS, Doherty ST.
Changes in temperature are known to produce apoptosis in adipocytes. This study examines the use of a non-invasive treatment that applies 1060 nm laser energy transcutaneously to hyperthermically induce disruption of fat cells in the abdomen.
Thirty-five subjects received application of 1060 nm laser on the abdomen for fat reduction. Ultrasound images and high-resolution two-dimensional photography were recorded at baseline, 6 weeks, and 12 weeks post treatment. Subjects maintained a stable diet and exercise routine throughout the course of the study. Weight was recorded at baseline and each follow-up visit. Three board certified dermatologists were trained as blinded evaluators and tasked with identifying before and after photographs from randomized, paired baseline, and 12-week photographs. Ultrasound images were used to measure the fat thickness change from baseline at 6 and 12 weeks. Level of patient satisfaction was graded at 12 weeks using a 6 point Likert scale.
23% of subjects were Fitzpatrick IV-VI. Blinded evaluators correctly identified the post-treatment photograph 95% of the time (88%, 97%, and 100%). Mean reduction in fat layer thickness from baseline was statistically significant (P less than 0.001) at both 6 weeks (1.5 +/-1.23 mm) and 12 weeks (2.65 +/-1.41 mm). Mean weight change was +0.1 lb. Side effects were mild to moderate including edema, tenderness, and induration mostly resolving within 1-3 weeks post treatment. No serious adverse events were reported.
1060 nm based laser treatment can consistently reduce the fat contour in the abdomen with an excellent safety profile in all skin types. The study met all three of its prospectively defined endpoints of success. J Drugs Dermatol. 2018;17(1):
106-112.J Drugs Dermatol. 2017 Jan 1;16(1):48-52.
1060 nm Diode Hyperthermic Laser Lipolysis:The Latest in Non-Invasive Body Contouring.
Schilling L, Saedi N, Weiss R.
Non-invasive body contouring is becoming increasingly popular in the United States. Using the 1060 nm diode laser to achieve hyperthermic temperatures within the adipose tissue with subsequent lipolysis is one of the most recent advancements in this field and is the first of its kind. This wavelength was carefully chosen to effectively target the unwanted adipocytes while sparing the overlying skin and adnexae. Appreciable results are achieved after a single treatment, and these results are comparable to other non-invasive technologies. The 25-minute procedure is well tolerated among patients, with no downtime required. This versatile system allows for treatment of multiple body sites, which can be customized for a particular patient’s needs. Herein, we discuss in detail the mechanism of action, efficacy, and safety of 1060 nm diode hyperthermic laser lipolysis. Amongst the various body contouring modalities available today, the 1060 nm diode hyperthermic laser is a worthy addition providing a safe, quick, and effective non-invasive fat reduction option for patients. <em>J Drugs Dermatol. 2017;16(1):48-52.
- Bingol UA, Cinar C. Laser lipolysis without suction: reality or myth? Photomed Laser Surg. 2014 Nov;32(11):642-5.
- Bass LS, Doherty ST. Safety and Efficacy of a Non-Invasive 1060 nm Diode Laser for Fat Reduction of the Abdomen. J Drugs Dermatol. 2018 Jan 1;17(1):106-112.
- Schilling L, Saedi N, Weiss R. 1060 nm Diode Hyperthermic Laser Lipolysis:The Latest in Non-Invasive Body Contouring. 106-112.J Drugs Dermatol. 2017 Jan 1;16(1):48-52.
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